Pharmacokinetics Of Aluminum Hydroxide

A small amount of aluminum hydroxide is converted into soluble aluminum chloride in the stomach, which is absorbed from the gastrointestinal tract and excreted in the urine. Most of it is excreted from the feces in the form of aluminum phosphate, aluminum carbonate and fatty acid salts; the onset of aluminum hydroxide is slow, and the length of the effect in the stomach is related to the speed of gastric emptying. The effect of taking the medicine on an empty stomach can last for 20 to 30 minutes, and the effect of taking the medicine 1 to 2 hours after a meal can be extended to 3 hours.